Evaluasi Stabilitas Formulasi Krim Ekstrak Propolis Geniotrigona thoracica

Paula Mariana Kustiawan (Program Studi Sarjana Farmasi, Fakultas Farmasi, Universitas Muhammadiyah Kalimantan Timur, Jl. Juanda No. 15 Kota Samarinda 75124, Indonesia)
Deasy Nur Chairin Hanifa (Program Studi Sarjana Farmasi, Fakultas Farmasi, Universitas Muhammadiyah Kalimantan Timur, Jl. Juanda No. 15 Kota Samarinda 75124, Indonesia)
Muhammad Alib Batistuta (Program Studi Sarjana Farmasi, Fakultas Farmasi, Universitas Muhammadiyah Kalimantan Timur, Jl. Juanda No. 15 Kota Samarinda 75124, Indonesia)
Azzah Fatimah Zulfa (Program Studi Sarjana Farmasi, Fakultas Farmasi, Universitas Muhammadiyah Kalimantan Timur, Jl. Juanda No. 15 Kota Samarinda 75124, Indonesia)

Journal Syifa Sciences and Clinical Research (JSSCR)
Vol 4, No 3 (2022): Volume 4 Edisi 3 2022

Methanolic extract of Geniotrigona thoracica propolis has been reported as strong antioxidant. This potential can be applied as cream product. This aims of this study is to evaluate the physical stability of the formulation of G. thoracica propolis cream which has antioxidant activity. The extract was obtained from propolis through the maceration method and then formulated into a cream dosage form. Detemination of the physical properties of cream product were included organoleptic test, homogeneity test, pH test, dispersibility test and adhesion test. The results of the stability evaluation of G. thoracica propolis cream showed a light brown color consistency, a weak characteristic odor and a soft semi-solid texture, homogeneous, pH 7, 6.5 cm spreadability and 260 seconds stickiness. The preparation of the G. thoracica propolis extract cream met the requirements of the physical tests performed. In addition, the G. thoracica propolis has good physical stability during storage.