Aceh International Journal of Science and Technology
Vol 2, No 3 (2013): December 2013

Tyrosinase Inhibition Type of Isolated Compounds Obtained from Pachyrhizus erosus

Endang Lukitaningsih (Unknown)
Muhammad Bahi (Unknown)
Ulrike Holzgrabe (Unknown)

Article Info

Publish Date
02 Jan 2014

Abstract

Abstract - In Indonesia, Bengkoang (Phacyrhizus erosus) have been used as one of cosmetics especially as sun screening and skin whitening materials. Six active compounds in Bengkoang with antioxidant and skin whitening activities have been isolated, namely daidzein, daidzin, genistin, (8,9)-furanyl-pterocarpan-3-ol, 4-(2-(furane-2-yl)ethyl)-2-methyl-2,5-dihydro-furane-3-carbaldehyde and 2-butoxy-2,5-bis(hydroxymethyl)-tetrahydrofurane-3,4-diol. According to literatures, the type of their tyrosinase inhibitory activity has not yet reported. The determination of whitening activity of each compound was evaluated by the evaluation of Lineweaver-Burk plot. The result showed that five compounds had competitive inhibitory activity and 8,9-furanyl-pterocarpan-3-ol showed a non-competitive inhibition. Keywords: Pachyrhizus erosus, tyrosinase, competitive inhibition and non-competitive inhibition

Copyrights © 2013




Citation Download
RIS
EndNote, Reference Manager, ProCite
BibTex
Latex, Jabref
Full PDF
431.611 KB
Original Source
Download Original
Google Scholar
Check in Google Scholar
Journal Info
Aceh International Journal of Science and Technology
Website

Abbrev

AIJST

Publisher

Universitas Syiah Kuala

Subject

Agriculture, Biological Sciences & Forestry Chemical Engineering, Chemistry & Bioengineering Control & Systems Engineering Decision Sciences, Operations Research & Management Earth & Planetary Sciences

Description

Aceh International Journal of Science & Technology (AIJST) is published by the Graduate School of Syiah Kuala University (PPs Unsyiah) and the Indonesian Soil Science Association (Himpunan Ilmu Tanah Indonesia, Komda Aceh). It is devoted to identifying, mapping, understanding, and interpreting new ...