Journal of Global Pharma Technology
Volume 11 Issue 2: 2019

Synthesis and Characterization of Some Heterocyclic Compounds and Evaluation of their Antioxidant Activity

Auhood Kadhim Zaid (Unknown)



Article Info

Publish Date
16 Nov 2016

Abstract

This study is concerned with the synthesis and characterization of five derivatives of two groups of heterocyclic compounds, dihydroprimidine (DHPM) and imidazole. The DHPM derivatives were [benzyl 6-methyl-4-(naphthalen-2-yl)-2-thioxo-1,2,3,4-tetrahydropyrimidine-5-carboxylate (1a)], [benzyl 6-methyl-4-(naphthalen-2-yl)-2-oxo-1,2,3,4-tetrahydropyrimidine-5-carboxylate (2a)] and [benzyl 4-(1-hydroxynaphthalen-2-yl)-6-methyl-2-oxo-1,2,3,4-tetrahydropyrimidine-5-carboxylate (3a)] and the imidazole compounds were [1,4-bis(4-(4-bromophenyl)-1-(3-chlorophenyl)-1H-imidazol-2-yl) benzene (1b)] and [1,4-bis(4-(4-bromophenyl)-1-phenyl-1H-imidazol-2-yl)benzene (2b)]. Biological testing revealed the prepared compounds to have antioxidant properties. Keywords: Antioxidants, Heterocyclic compounds, Dihydroprimidine, Imidazole, Biological activity.

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Journal Info

Abbrev

jgpt

Publisher

Subject

Medicine & Pharmacology

Description

ournal of Global Pharma Technology is a monthly, open access, Peer review journal of Pharmacy published by JGPT Journal publishes peer-reviewed original research papers, case reports and systematic reviews. The journal allows free access to its contents, which is likely to attract more readers and ...