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Auhood Kadhim Zaid
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Medicine & Pharmacology

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Synthesis and Characterization of Some Heterocyclic Compounds and Evaluation of their Antioxidant Activity Auhood Kadhim Zaid
Journal of Global Pharma Technology Volume 11 Issue 2: 2019
Publisher : Journal of Global Pharma Technology

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Abstract

This study is concerned with the synthesis and characterization of five derivatives of two groups of heterocyclic compounds, dihydroprimidine (DHPM) and imidazole. The DHPM derivatives were [benzyl 6-methyl-4-(naphthalen-2-yl)-2-thioxo-1,2,3,4-tetrahydropyrimidine-5-carboxylate (1a)], [benzyl 6-methyl-4-(naphthalen-2-yl)-2-oxo-1,2,3,4-tetrahydropyrimidine-5-carboxylate (2a)] and [benzyl 4-(1-hydroxynaphthalen-2-yl)-6-methyl-2-oxo-1,2,3,4-tetrahydropyrimidine-5-carboxylate (3a)] and the imidazole compounds were [1,4-bis(4-(4-bromophenyl)-1-(3-chlorophenyl)-1H-imidazol-2-yl) benzene (1b)] and [1,4-bis(4-(4-bromophenyl)-1-phenyl-1H-imidazol-2-yl)benzene (2b)]. Biological testing revealed the prepared compounds to have antioxidant properties. Keywords: Antioxidants, Heterocyclic compounds, Dihydroprimidine, Imidazole, Biological activity.
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