Acta Chimica Asiana
Vol. 6 No. 1 (2023)

C-prenylation of 1,3 dihydroxyxanthone: synthesis, characterization and antibacterial activity

Yuanita, Emmy (Unknown)
Jannah, Baiq Khaeratul (Unknown)
Ulfa, Maria (Unknown)
Sudirman (Unknown)
Ningsih, Baiq Nila Sari (Unknown)
Dharmayani , Ni Komang Tri (Unknown)

Article Info

Publish Date
25 Feb 2023

Abstract

Prenylated 1,3-dihydroxyxanthone has been successfully synthesized using Prenyl bromide and KOH. Characterization of the synthesized compound using Infra Red (IR) and Nuclear Magnetic Resonance (1H-NMR) showed that monosubstituted c-prenylation was occurred at carbon number 2 to form 1,3-dihydroxy-2-prenylxanthone. The synthesis result was a yellow-brown paste with a yield of 43.09%. This prenylated 1,3-dihydroxyxanthone had moderate antibacterial activity against Escherichia coli with an inhibition zone > 5 mm at a concentration of 15%.

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Journal Info
Acta Chimica Asiana
Website

Abbrev

ACA

Publisher

Universitas Mataram

Subject

Chemistry

Description

Acta Chimica Asiana (online ISSN 2550-0503, print ISSN 2550-049x) is a peer-reviewed, open access journal that publishes high-quality original research articles as well as review articles in all areas of Chemistry and Chemical Engineering. Significant finding that is insufficient to be presented as ...