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All Journal Acta Chimica Asiana
Jannah, Baiq Khaeratul
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Chemistry

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C-prenylation of 1,3 dihydroxyxanthone: synthesis, characterization and antibacterial activity Yuanita, Emmy; Jannah, Baiq Khaeratul; Ulfa, Maria; Sudirman; Ningsih, Baiq Nila Sari; Dharmayani , Ni Komang Tri
Acta Chimica Asiana Vol. 6 No. 1 (2023)
Publisher : The Indonesian Chemical Society, Chapter Nusa Tenggara and The University of Mataram

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.29303/aca.v6i1.149

Abstract

Prenylated 1,3-dihydroxyxanthone has been successfully synthesized using Prenyl bromide and KOH. Characterization of the synthesized compound using Infra Red (IR) and Nuclear Magnetic Resonance (1H-NMR) showed that monosubstituted c-prenylation was occurred at carbon number 2 to form 1,3-dihydroxy-2-prenylxanthone. The synthesis result was a yellow-brown paste with a yield of 43.09%. This prenylated 1,3-dihydroxyxanthone had moderate antibacterial activity against Escherichia coli with an inhibition zone > 5 mm at a concentration of 15%.
Co-Authors Dharmayani , Ni Komang Tri Emmy Yuanita Maria Ulfa Ningsih, Baiq Nila Sari Sudirman