Effect Of Intaking High-Fat Diet On White Rat’s (Rattus norvegicus)Blood Lipid Profil

Made Subawa Harsa (Bagian Ilmu Faal Fakultas Kedokteran Universitas Wijaya Kusuma Surabaya)

Jurnal Ilmiah Kedokteran Wijaya Kusuma
Vol 3, No 1 (2014): Edisi Maret 2014

Obesity and metabolic syndrom are characterized by dislipidemia. One of methods that is performed to increase body fat contents is by intaking of high-fat diet. The purpose of this study was to demonstrate the effect of a dietary intake of high-fat on the lipid profile (total cholesterol, HDL, LDL, and triacylglycerol) in white rat (Rattus norvegicus). This research was tested on 30 white rats that were divided into 2 randomized groups, and were treated for 4 weeks. Group 1 (K1) : was treated with standard diet, (K2) : with standard and high-fat diet. The results showed that intaking high-fat diet increases the total cholesterol content, triacylglycerol, LDL cholesterol, and decreases HDL cholesterol content.