Majalah Kesehatan Indonesia
Vol. 4 No. 1: April 2023

Relationship between Soluble Fms-Like Tyrosine Kinase-1 (Sflt-1) Levels in Preeclamptic Mothers with Asphyxia

Wahida Wahida (Midwifery Department Health Polytechnic Ministry of Health Mamuju.)
Gusriani Gusriani (Midwifery Department Faculty of Health Sciences Borneo Tarakan University.)



Article Info

Publish Date
25 Apr 2023

Abstract

Soluble Fms like tyrosine kinase 1 (sFlt-1) is one of the markers that play a role in the pathogenesis of pregnancy-induced hypertension. The research aimed to determine the relationship between sFlt-1 level and asphyxia. The samples were preeclampsia inpartu consisting of 22 people, and normal pregnancy women consisting of 18 people. An analytic observational study with cross-sectional was conducted. The level of sFlt-1 was examined using ELISA. Statistic analysis used Kruskal Wallis test, One-way Anova test and Pearson correlation test.  The results showed the facts of the study in the preeclampsia and control groups were not different (p> 0.05). In the preeclampsia group, and the control group (7.876 ± 3.792 ng / mL; p <0.05). There was a difference between sFlt-1 levels and the incidence of asphyxia (p = 0.003) in the preeclampsia group, whereas in the control group no relationship was found between sFlt-1 levels and asphyxia (p> 0.05).

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Journal Info

Abbrev

makein

Publisher

Subject

Humanities Health Professions Medicine & Pharmacology Nursing Public Health

Description

Majalah Kesehatan Indonesia (MAKEIN) with registered ISSN 2745-6498 (Print) and ISSN 2745-8008 (online), is an interdisciplinary journal that publishes material on all aspects of public health science. This MAKEIN provides the ideal platform for the discussion of more sophisticated public health ...