Jurnal Ilmiah Ibnu Sina (JIIS): Ilmu Farmasi dan Kesehatan
Vol 8 No 1 (2023): JIIS

FORMULASI GEL HAND SANITIZER EKSTRAK DAUN PALIASA (Kleinhovia hospita Linn) DENGAN GELLING AGENT HPMC

Yetri Elisya (Jurusan Farmasi, Politeknik Kesehatan Kemenkes Jakarta II)
Wardiyah Wardiyah (Jurusan Farmasi, Politeknik Kesehatan Kemenkes Jakarta II)
Junaedi Junaedi (Jurusan Farmasi, Politeknik Kesehatan Kemenkes Jakarta II)
Farah Hamidah (Jurusan Farmasi, Politeknik Kesehatan Kemenkes Jakarta II)



Article Info

Publish Date
31 Mar 2023

Abstract

Gel hand sanitizer is a novel product formula that can be utilized as a cost-effective and portable replacement for hand washing soap. One of the plants whose leaves can be used as a central component of hand sanitizer gel is the Paliasa plant (Kleinhovia hospita Linn). Staphylococcus and Escherichia coli resist the antimicrobial effects of alkaloids, tannins, and saponins. To create the hand sanitizer gel, three different concentrations of the HPMC gelling ingredient were used: 1%, 2%, and 3%. Variations in the amount of HPMC used in each formulation impact the gel's characteristics, particularly its viscosity, spreadability, and adherence. Following the cycle test, the three formulations' viscosity decreased, but their pH, spreadability, and stickiness increased. There was no significant difference between the stability test on day 0 and day 12 for pH, viscosity, spreadability, and gel adhesion, according to testing utilizing the paired sample T-test. > 0.05.

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Journal Info

Abbrev

JIIS

Publisher

Subject

Medicine & Pharmacology

Description

Jurnal Ilmiah Ibnu Sina (JIIS): Ilmu Farmasi dan Kesehatan is a broad-based primary journal covering all branches of pharmacy and its sub-disciplines that contains complete research articles, short communication and review articles. JIIS is a forum for the publication of quality and original works ...