Pharmaciana: Jurnal Kefarmasian
Vol 13, No 1 (2023): Pharmaciana

Evaluation and clinical activity test of various concentrations of peel-off gel mask of robusta coffee seed extract (Coffea canephora) as anti-aging

Angga Saputra Yasir (Institut Teknologi Sumatera)
Agesta Yesti Renita (Malahayati University)
Tutik Tutik (Unknown)



Article Info

Publish Date
03 Apr 2023

Abstract

 Robusta coffee beans contain antioxidant compounds having anti-aging properties. This study aims to determine the content of secondary metabolites in robusta coffee bean extract, anti-aging effectiveness, and the best peel-off gel mask preparation concentration. The extraction method in this study used maceration with 96% ethanol as solvent. The extraction results were carried out by phytochemical screening and formulation of peel-off gel mask preparations, then tested for anti-aging effectiveness using 12 female volunteers and observed signs of aging, including pores, spots, wrinkles, and moisture for four weeks. Robusta coffee bean extraction results obtained a yield of 9.2%. The results of phytochemical screening showed that robusta coffee bean extract contains flavonoid compounds, alkaloids, tannins, and saponins. The results of the evaluation of the 0.5% formula of robusta coffee bean extract were the most preferred by volunteers. The best effectiveness and concentration test results were found in the peel-off gel mask preparation of 2% robusta coffee bean extract formula (F2) compared to blank and F1 (p-value <0.05). The percentage of improvement in the condition of the volunteers' skin, including pores, spots, wrinkles, and moisture, is 21.88 ± 4.22%, 21.57 ± 3.25%, 17.71 ± 2.44%, and 21.25 ± 3.62%, respectively.

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Journal Info

Abbrev

PHARMACIANA

Publisher

Subject

Medicine & Pharmacology

Description

Pharmaciana is a scientific journal published by the University of Ahmad Dahlan worked closely with Ikatan Apoteker Indonesia (IAI). Pharmaciana published three times a year, namely March, July and November. with ISSN 2088-4559 and e-ISSN 2477-0256. The article published in the Journal Pharmaciana ...