PCJN Pharmaceutical and Clinical Journal of Nusantara
Vol. 1 No. 01 (2022): PCJN: Pharmaceutical and Clinical Journal of Nusantara

TESTING THE EFFECTIVENESS OF BIDARA LEAF ETHANOL EXTRACT (Ziziphus mauritiana L.) IN GEL PREPARATIONS FOR BURN WOUNDS IN MALE RABBIT (Oryctolapus cuniculus)

Sulasmi Sulasmi (Institut Kesehatan Deli Husada Delitua)
Angga Nugraha Sanjaya (Institut Kesehatan Deli Husada Delitua)
Sofia Elia Sari Bangun (Institut Kesehatan Deli Husada Delitua)
Cucu Arum Dwi Cahaya (Institut Kesehatan Medistra Lubuk Pakam)



Article Info

Publish Date
24 Nov 2022

Abstract

Abstract Bidara plants have many benefits in the treatment of sore skin, ulcers, and burns. Burns are a form of tissue damage or loss caused by contact with a heat source such as fire, hot water, electricity, radiation, or corrosive substances. This study aims to determine the effectiveness of the ethanol extract of bidara leaf in healing burns in male rabbits compared to bioplacenta. This study used an experimental method of maceration extraction using 96% ethanol. To test the effect of burns, 15 test animals were grouped into five groups, each of which used three test animals. The treatment group was a gel-based negative control group, a positive bioplacenta control group, and a treatment group with bidara leaf ethanol extract at concentrations of 5%, 10%, and 15%. The results of the research on the effectiveness of healing burns in the three formulations, namely a concentration of 15%, showed faster healing of wound diameter in male rabbits compared to concentrations of 5% and 10% but were not more effective when compared to bioplacenta ointment. Keywords: Bidara leaf ethanol extract, burns, ointment and bioplacenton

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Journal Info

Abbrev

pcjn

Publisher

Subject

Health Professions Medicine & Pharmacology Neuroscience Nursing Public Health

Description

Journal that publishes Focus & Scope research articles, which include: Pharmaceutical Biology Pharmaceutical Technology Pharmaceutical Chermistry Pharmacology Clinical Pharmacy Microbiology Pharmacy This journal is published by the Nusantara Scientific Journal , which is published March, July, and ...