Isolasi dan karakterisasi senyawa metabolit sekunder dari bakteri laut Streptomyces sp.

Muhammad Bahi (Jurusan Kimia, Fakultas Matematika dan Ilmu Pengetahuan Alam, Univesitas Syiah Kuala, Banda Aceh, 23111 Indonesia.)

Depik Jurnal Ilmu-Ilmu Perairan, Pesisir dan Perikanan
Vol 1, No 3 (2012): December 2012

Abstract: Streptomyces is one of bacterial genus which has been considered as a potential source of many novel antibiotics from both terrestrial and marine microorganism. In this paper, four secondary metabolites have been isolated and characterized from a marine Streptomyces sp. B5798, namely phydroxyphenylacetic acid (2), indole-3-carboxylic acid (3), indole-3-acetic acid (4), and Macrolactin A (5), respectively. Two of them are common compounds, namely indole-3-carboxylic acid (3) and indole-3-acetic acid (4). The 3,4 dihydroxybenzaldehyde is a degradation product of phydroxyphenylacetic (2) in microorganism. Macrolactin A (5) showed cytotoxicity against brine shrimps test (A. salina). All structures of the isolated compounds were elucidated based on spectroscopic and mass spectrometry data.