This paper will analyse the discourse of Islamic reconciliation and modern science experienced a debate between Nidhal Guessoum and Ismail Al-Faruqi. Guessoum's thought bridges religion with science in using of quantum approach method to integrate both of them. The research results show that quantum approach itself is based on three principles: the principle of non-contradiction, the principle of multi-layered interpretation, the principle of falsification-theistic. Ismail al-Faruqi has a brilliant idea in finding solutions to the problems of muslims’ life. The idea is inseparable from the concept of tauhid as the essence of Islam. his idea of the Islamization of science as knowledge meant the Islamization of modern science by carrying out scientific activities such as elimination, change, reinterpretation and adjustment of its components
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