Journal of Pharmaceutical and Sciences.
JPS Volume 6 Nomor 2 (2023)

Review Artikel: Pemanfaatan Kimia Komputasi Dengan Berbagai Metode Dalam Menentukan Desain Senyawa Baru

Lina Nurfadhila (Universitas Singaperbangsa Karawang, Karawang, Jawa Barat, Indonesia)
Diah Muldianah (Universitas Singaperbangsa Karawang, Jawa Barat, Indonesia.)
Diany Aprillia Nurdimayanthi (Universitas Singaperbangsa Karawang, Jawa Barat, Indonesia.)
Dinda Shafira Rahmawati (Universitas Singaperbangsa Karawang, Jawa Barat, Indonesia.)
Hajar Hartati (Universitas Singaperbangsa Karawang, Jawa Barat, Indonesia.)
Hana Fadhilah (Universitas Singaperbangsa Karawang, Jawa Barat, Indonesia.)



Article Info

Publish Date
23 Jun 2023

Abstract

Research in the pharmaceutical field is helped by the development of technology and science, one of which is in the field of medicinal chemistry related to drug discovery and treatment development design. Computation is one of the techniques in drug development with molecular docking and Quantitative Structure Activity (HKSA) methods which include synthesis, purification, design, identification and activity testing of a compound. The method used is to conduct studies from various sources with a total of 29 journals found on various official websites and which are used as the main journal as many as 10 journals with various computational techniques, namely molecular docking, PM3 semiempirical, AM1 semiempirical, in silico and HKSA. The potential of compounds from various literatures results in several medicinal purposes, namely as anticancer, antimalarial, antibacterial, anti-HIV and covid prevention. The potential of these compounds is obtained from different chemical compounds. The compounds used in this journal include compounds derived from 1,3-dibenzolythiourea, quinine compounds, fluoroquinolone parent compounds, chalcone-derived compounds, kuwanon compounds and their derivatives, leonurin compounds and their derivatives, compounds derived from N-(Benzoil)-N'-phenylthiourea, Beta asaron-derived compounds, meisiindigo-derived compounds and quercetin compounds.

Copyrights © 2023






Journal Info

Abbrev

jps

Publisher

Subject

Agriculture, Biological Sciences & Forestry Biochemistry, Genetics & Molecular Biology Chemical Engineering, Chemistry & Bioengineering Chemistry Immunology & microbiology Materials Science & Nanotechnology Medicine & Pharmacology Nursing Public Health

Description

Journal of Pharmaceutical and Sciences (JPS) with e-ISSN: 2656-3088 is a scholarly peer-reviewed open access journal related to Pharmaceutics, Pharmacology, biotechnology, Pharmacognosy & Phytochemistry, Pharmaceutical Chemistry, Pharmaceutical Biotechnology, Pharmacy practice, Pharmacogenomics, ...