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Lina Nurfadhila

Universitas Singaperbangsa Karawang, Karawang, Jawa Barat, Indonesia

Author-ID : 6257092

Agriculture, Biological Sciences & Forestry Biochemistry, Genetics & Molecular Biology Chemical Engineering, Chemistry & Bioengineering Chemistry Immunology & microbiology Materials Science & Nanotechnology Medicine & Pharmacology Nursing Public Health

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Molecular Docking Senyawa Yang Berpotensi Sebagai Antikanker Payudara: Literature Review Anisa Fauziah; Adelia Fatharani; Cindhy Maulida Nurawaliah; Faizal Auladi Rivianto; Irene Virda Sakina; Marsah Rahmawati; Lina Nurfadhila
Journal of Pharmaceutical and Sciences JPS Volume 6 Nomor 2 (2023)
Publisher : Fakultas Farmasi Universitas Tjut Nyak Dhien

Cancer is a degenerative disease that has claimed many victims. Currently breast cancer is the second most common cancer that causes death after lung cancer and is the most common cancer suffered by women. Treatment of breast cancer is generally done with chemotherapy, radiotherapy, hormone therapy and surgery. Several synthetic drugs have been used to inhibit the growth of cancer cells. However, these drugs have dangerous side effects for the body so other alternatives are needed, including developing drugs derived from plants. To predict the activity of compounds from plants that have potential as anti-breast cancer, the molecular docking method was used. This review aims to inform compounds that have the potential as anti-breast cancer based on the results of molecular docking. The research method used was a literature study of 15 journals searched on the Google Scholar and Google databases related to molecular docking of breast anticancer compounds. The results of the review show that several compounds have the potential to inhibit breast cancer receptors including mangiferin compounds which are the best at inhibiting HER-2 receptors, quercetin glycoside compounds which are the best at inhibiting Bcl-2 receptors, quinine compounds which are the best at inhibiting ER-α receptors, compounds 6,7 -dihydro-17-hydroxyerisotrin is the best at inhibiting EGFR receptors, curcumin compounds are the best at inhibiting COX-2 receptors and eugenol compounds are the best at inhibiting ER-β receptors.

Review Artikel: Pemanfaatan Kimia Komputasi Dengan Berbagai Metode Dalam Menentukan Desain Senyawa Baru Lina Nurfadhila; Diah Muldianah; Diany Aprillia Nurdimayanthi; Dinda Shafira Rahmawati; Hajar Hartati; Hana Fadhilah
Journal of Pharmaceutical and Sciences JPS Volume 6 Nomor 2 (2023)
Publisher : Fakultas Farmasi Universitas Tjut Nyak Dhien

Research in the pharmaceutical field is helped by the development of technology and science, one of which is in the field of medicinal chemistry related to drug discovery and treatment development design. Computation is one of the techniques in drug development with molecular docking and Quantitative Structure Activity (HKSA) methods which include synthesis, purification, design, identification and activity testing of a compound. The method used is to conduct studies from various sources with a total of 29 journals found on various official websites and which are used as the main journal as many as 10 journals with various computational techniques, namely molecular docking, PM3 semiempirical, AM1 semiempirical, in silico and HKSA. The potential of compounds from various literatures results in several medicinal purposes, namely as anticancer, antimalarial, antibacterial, anti-HIV and covid prevention. The potential of these compounds is obtained from different chemical compounds. The compounds used in this journal include compounds derived from 1,3-dibenzolythiourea, quinine compounds, fluoroquinolone parent compounds, chalcone-derived compounds, kuwanon compounds and their derivatives, leonurin compounds and their derivatives, compounds derived from N-(Benzoil)-N'-phenylthiourea, Beta asaron-derived compounds, meisiindigo-derived compounds and quercetin compounds.

Metode Analisis Cemaran Mikroba pada Makanan : Review Artikel Aditia Putra Tama; Vina Luthfiana Hasna; Khamairah Azzahrawaani Hermawan; Marsah Rahmawati Utami; Lina Nurfadhila
Journal of Pharmaceutical and Sciences JPS Volume 6 Nomor 2 (2023)
Publisher : Fakultas Farmasi Universitas Tjut Nyak Dhien

Food is one of the important things in the sustainability of human life. The main function of food for humans is to meet the nutritional needs of the body, where these nutrients must be met according to gender, age, daily physical activity, and body weight. As the main and basic function of food itself, in order to be a good source of nutrients and energy, of course, the food must be ensured to be safe, clean, does not contain harmful food-enhancing ingredients, and is free from sources of disease. The source of this disease can arise from food that has been contaminated, one of which is food contaminated with microbial contamination. This article aims to inform the analysis of microbial contamination methods in various foods. The method used in writing this article review is to search for several references in the form of scientific journals or scientific articles from research with the keyword microbial contamination analysis.

Co-Authors Adelia Fatharani Aditia Putra Tama Anisa Fauziah Cindhy Maulida Nurawaliah Diah Muldianah Diany Aprillia Nurdimayanthi Dinda Shafira Rahmawati Faizal Auladi Rivianto Hajar Hartati Hana Fadhilah Irene Virda Sakina Khamairah Azzahrawaani Hermawan Marsah Rahmawati Marsah Rahmawati Utami Vina Luthfiana Hasna

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