Pharmacon
Vol 20, No 1 (2023)

Uji Aktivitas Wound Healing Ekstrak Etanol Buah Averrhoa bilimbiL. (Belimbing Wuluh) pada Mencit Putih Jantan (Mus musculus)

Rahmayati Rusnedy (STIFAR RIAU)
Mira Febrina (sekolah tinggi ilmu farmasi riau)
Cindy Patika Sari (sekolah tinggi ilmu farmasi riau)



Article Info

Publish Date
01 Jul 2023

Abstract

Wound healing is a complex process, delays in wound healing increase the chances of infection, improper healing, and unpleasant scarring. Belimbing wuluh (Averrhoa bilimbi L.) fruit contains various active compounds that are beneficial to health and have the potential to be used as medicinal preparations for treating wounds. In this test, incisions were made on the skin of the mice's back area using a scalpel 1 cm long and 0.3 cm deep. Observation of the length of the incision was carried out every day for 12 days using a caliper. Significant wound healing activity was observed from administration of 10% concentration of ethanol extract of belimbing wuluh (Averrhoa bilimbi L.) fruit which contains chemical compounds such as flavonoids, saponins, tannins and triterpenoids as well as minerals, one of which is zinc and Vitamin C is also proven to help speed up the healing process of incisions with a percentage of wound healing on day 12, which is 100%, the same percentage value as the group of test animals given Povidone Iodine 10% (Betadine®) as a comparator drug. The presence of zinc (zinc) and vitamin C in the extract of star fruit (Averrhoa bilimbi L.), is predicted to also contribute to the wound healing process in this test.

Copyrights © 2023






Journal Info

Abbrev

pharmacon

Publisher

Subject

Health Professions Medicine & Pharmacology

Description

Pharmacon: Jurnal Farmasi Indonesia is a collection of publication journals, covering all aspects of Pharmaceutical sciences, including Technology of Formulations, Excipients Optimization, Extract and Herbal Standardizations, Pharmacological activity determination on natural sources, Drug Synthesize ...