Communications in Science and Technology
Vol 8 No 1 (2023)

Fabrication of glutathione-modified gold nanoparticles as 3-chloropropane-1,2-diol sensor

Faramitha, Yora (Unknown)
Barori, Fadhlurrahman Rafi (Unknown)
Dimawarnita, Firda (Unknown)
Siswanto (Unknown)
Aqoma, Havid (Unknown)
Nugraha, Adam F (Unknown)
Ferdiansyah, Alfian (Unknown)



Article Info

Publish Date
11 Jul 2023

Abstract

Refined palm oil products may contain a harmful substance called as 3-monochloropropane-1,2-diol (3-MCPD), which can potentially be carcinogenic if consumed in excess. The determination of 3-MCPD depends on the sophisticated machine and highly skilled technicians but it is time-consuming. A simple method that proposes rapid detection remains a challenge. Hence, this research aims to develop a colorimetric-based rapid detection sensor using gold nanoparticles functionalized with a ligand, glutathione (GSH) to be bound to 3-MCPD. Varied concentrations of GSH were evaluated to obtain stable GSH-AuNPs. The characterization results showed that the composition of the stable GSH-AuNPs has been achieved by 250 µL of 0.02 M GSH addition. A stable GSH-AuNPs was ruby red with surface plasmon resonance (SPR) band at 520 nm and an average nanoparticle size of 30 nm. The indication for detection of 3-MCPD was marked by the decrease in the absorbance intensity. Thus, GSH-AuNPs have potential to be developed for the 3-MCPD sensor application.

Copyrights © 2023






Journal Info

Abbrev

cst

Publisher

Subject

Engineering

Description

Communication in Science and Technology [p-ISSN 2502-9258 | e-ISSN 2502-9266] is an international open access journal devoted to various disciplines including social science, natural science, medicine, technology and engineering. CST publishes research articles, reviews and letters in all areas of ...