Bioscientist : Jurnal Ilmiah Biologi
Vol 11, No 1 (2023): June

Kapasitas Total Antioksidan dan Uji Toksisitas Ekstrak Bunga Kecombrang (Etlingera elatior (Jack) R.M.Sm)

Faiz Agung Hermawan (Program Studi Sarjana Kedokteran, Fakultas Kedokteran, Universitas Tarumanagara, Jalan Letjen S. Parman Nomor 1, Jakarta Barat, Daerah Khusus Ibukota Jakarta 11440)
Frans Ferdinal (Bagian Biokimia dan Biologi Molekular, Fakultas Kedokteran, Universitas Tarumanagara, Jalan Letjen S. Parman Nomor 1, Jakarta Barat, Daerah Khusus Ibukota Jakarta 11440)



Article Info

Publish Date
30 Jun 2023

Abstract

Oxidative stress is imbalance between antioxidant production and the formation of free radicals, which are involved in the development of degenerative diseases. Declining organ function is a symptom of degenerative diseases. The antioxidant helps protect the body from free radicals and prevent oxidative stress. Antioksidan classified into exogenous and endogenous. (Etlingera elatior (Jack) R.M.Sm) flower is known for its antioxidants. This study aimed to establish the toxicity and antioxidant features of kecombrang flower. Total antioxidant capacity test by Blois 1,1 Diphenyl-2Picryhydrazyl  (DPPH) method, toxicity test by Brine Shrimp Lethality Test (BSLT) method. After acquiring simplicia by grinding and aerating the flowers, the extract was obtained by the maceration process using methanol as the solvent and evaporation. The extract was then analyzed. The total antioxidant capacity test showed an IC50 of 931.53 g/mL, indicating that kecombrang flower has a low total antioxidant capacity. Based on the results of the toxicology tests, the LC50 value for the kecombrang flower extract was 612.66 g/mL, indicating that it possessed toxic properties. This study concluded that kecombrang flower extract was shown to have low antioxidant levels and potential antimitotic activity.

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Journal Info

Abbrev

bioscientist

Publisher

Subject

Agriculture, Biological Sciences & Forestry Biochemistry, Genetics & Molecular Biology Education Immunology & microbiology Social Sciences

Description

Bioscientist : Jurnal Ilmiah Biologi (BJIB), receiving and publishing article in the form of research (scientific article) in the field of biology education and utilization of biological research in learning. Moreover, this journal bridges the gap between research and practice, providing ...