Indonesian Journal of Biotechnology
Vol 28, No 3 (2023)

Effect of fluidised bed drying on ginsenoside content in hairy root cultures of Panax ginseng C.A. Meyer

James Setiabudi (Faculty of Biotechnology, University of Surabaya, Raya Kalirungkut, Kalirungkut, Surabaya 60293, Jawa Timur, Indonesia)
Komang Mega Oka Sri Bintang (Faculty of Biotechnology, University of Surabaya, Raya Kalirungkut, Kalirungkut, Surabaya 60293, Jawa Timur, Indonesia)
Stella Stacia Gani (Faculty of Biotechnology, University of Surabaya, Raya Kalirungkut, Kalirungkut, Surabaya 60293, Jawa Timur, Indonesia)
Pissa Christanti (PT. Bintang Toedjoe, Pulomas, Jakarta 13210, Indonesia)
Evanie Noer Putri (PT. Bintang Toedjoe, Pulomas, Jakarta 13210, Indonesia)
Se Chan Kang (Graduate School of Biotechnology, College of Life Sciences, Kyung Hee University, Yongin 17104, Republic of Korea)
Johan Sukweenadhi (Faculty of Biotechnology, University of Surabaya, Raya Kalirungkut, Kalirungkut, Surabaya 60293, Jawa Timur, Indonesia)



Article Info

Publish Date
30 Sep 2023

Abstract

Korean Ginseng (Panax ginseng C.A. Meyer) is a high‐value herb with many pharmacological benefits due to its primary active compound, ginsenosides. The most ginsenosides are known to be thermolabile and susceptible to degradation at high‐temperature processing. Our previous studies revealed that the optimum parameters related to the P. ginseng tissue culture protocol, particularly for hairy root propagation of Cultured Roots of Mountain Ginseng (CRMG)‐88, was using a lab‐scale bioreactor. The next stage involves screening for a suitable post‐harvest treatment, i.e., drying, will be production of the best quality ginsenoside content. This study therefore aimed to examine the ginsenoside content by using a fluidised bed dryer (FBD) on the ginseng roots. Our results showed that FBD produced a significantly higher of total ginsenoside content (5.386 ± 1.167%), compared to control (3.750 ± 0.641%). FBD‐dried CRMG‐88 also appeared lighter in colour and more voluminous with a Loss on Drying (LOD) of 6.448 ± 1.900%. This study concluded that fluidised bed drying is superior in retaining ginsenoside content and has the potential for large‐scale application.

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Journal Info

Abbrev

ijbiotech

Publisher

Subject

Biochemistry, Genetics & Molecular Biology Immunology & microbiology Materials Science & Nanotechnology

Description

The Indonesian Journal of Biotechnology (IJBiotech) is an open access, peer-reviewed, multidisciplinary journal dedicated to the publication of novel research in all aspects of biotechnology, with particular attention paid to the exploration and development of natural products derived from ...