Background; Type II diabetes mellitus is often known as diabetes. Type II diabetes mellitus is a metabolic disorder characterized by an increase in blood sugar levels above the normal threshold. Objective; To determine the relationship between self-care and the quality of life of type II diabetes mellitus sufferers at Mitra Medika Medan General Hospital in 2015. Materials and Methods; The research design used in this research uses the Analytical Survey method with a Cross Sectional approach. The population in this study was type II diabetes mellitus sufferers, totaling 129 respondents. The sampling used was purposive sampling, namely taking samples for a purpose by determining certain characteristics that are considered representative of the population. The sampling was done using the Slovin technique, totaling 56 respondents. Results; Based on the results of the analysis using the Chi-Square test, it shows that the significant probability value (Asymp.Sig) of Self Care is 0.003
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