Jurnal Ilmiah Ibnu Sina (JIIS): Ilmu Farmasi dan Kesehatan
Vol 8 No 2 (2023): JIIS

PENGARUH KONSENTRASI ASAM HIALURONAT TERHADAP STABILITAS FISIK SALEP KOMBINASI EKSTRAK IKAN GABUS

Lelek Kipli (Unknown)
Mohamad Andrie (Universitas Tanjungpura)
Wintari Taurina (Universitas Tanjungpura)



Article Info

Publish Date
31 Oct 2023

Abstract

The combination of snakehead fish ointment is expected to have synergistic properties in wound healing. Variations in natural ingredients added to the formula will affect the stability of the preparation during its shelf life. Hyaluronic acid, as a humectant agent, is used to maintain stability and improve physical properties by increasing the consistency of the preparation and reducing the risk of syneresis. The test method in this study was the stability test of the intermediate at 30°C ± 2°C/ RH 65 ± 5 % for six months. The Parameters measured were spreadability, adhesion, and pH. The observations showed that all formulas met the physical characteristics of the ointment until the 1st month. The 0.25% hyaluronic acid concentration was the most stable formula, which maintained the stability of spreadability and adhesion up to the 1st-month test point.

Copyrights © 2023






Journal Info

Abbrev

JIIS

Publisher

Subject

Medicine & Pharmacology

Description

Jurnal Ilmiah Ibnu Sina (JIIS): Ilmu Farmasi dan Kesehatan is a broad-based primary journal covering all branches of pharmacy and its sub-disciplines that contains complete research articles, short communication and review articles. JIIS is a forum for the publication of quality and original works ...