Journal of Food and Pharmaceutical Sciences
Vol 7, No 3 (2019): J. Food Pharm. Sci

The Biochemistry, Toxicology, and Uses of the Pharmacologically Active Phytochemicals: Alkaloids, Terpenes, Polyphenols, and Glycosides

Chinaza Godswill Awuchi (Department of Physical Sciences, Kampala International University, Kampala, Uganda)



Article Info

Publish Date
27 Nov 2019

Abstract

The research focused on the biochemistry and the medicinal uses of alkaloids, terpenes,polyphenols, and glycosides. Several parts of plants such as bark, root, leaf, stem, etc. are being used torevert abnormalities back to normal, prevent illnesses, or allay symptoms. These plant parts containbioactive compounds such as terpenes, glycosides, polyphenols, and alkaloids. Alkaloids have a rangeof pharmacological activities such as antiasthma (e.g. ephedrine), anticancer (e.g. homoharringtonine),antimalarial (e.g. quinine). Other alkaloids possess stimulant (e.g. cocaine, caffeine, theobromine, nicotine)and psychotropic activities (e.g. psilocin), and have been widely used as recreational drugs orin entheogenic rituals. Alkaloids can be toxic too (e.g. tubocurarine, atropine). Although alkaloids act ondiverse metabolic systems in humans and animals, they almost uniformly induce a bitter taste. Thecharacteristics and number of the structures of phenol in polyphenols underlie the unique chemical,physical, and biological (metabolic, therapeutic, toxic, etc.) properties of specific members of the class;e.g. ellagitannin and tannic acid. Generally, foods often contain complex mixtures of polyphenols. Severalpolyphenolic extracts, such as from grape seeds, olive pulp, maritime pine bark, or grape skin, are sold asingredients for functional foods, cosmetics, and dietary supplements. Terpenoids and terpenes are theprimary components of the essential oils of most types of flowers plants. Essential oils are used widely asscents and fragrances in perfumery and also in traditional medicine, such as aromatherapy. Similarly,many plant glycosides are used as medicines. Amygdalin and laetrile (a synthetic derivative) wereinvestigated as potential drugs for cancer treatment and were promoted as alternative medicine;nevertheless, they are ineffective and dangerous. Pharmacologically active phytochemicals can haveuseful applications, as well as safety concerns.

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Journal Info

Abbrev

JFPS

Publisher

Subject

Biochemistry, Genetics & Molecular Biology Chemical Engineering, Chemistry & Bioengineering Immunology & microbiology Materials Science & Nanotechnology Medicine & Pharmacology Neuroscience

Description

Journal of Food and Pharmaceutical Sciences offers scientists, researchers, and other professionals to share knowledge of scientific advancements. The journal will publish original research articles, review articles, short communication, and letter to editor. The area of focus should cover all ...