FEATURES OF THE COURSE OF DIABETIC NEUROSTEOARTHROPATHY IN PATIENTS WITH TYPE 2 DIABETES MELLITUS

Djuraeva Zilola Aramovna (Assistant of the Department of Endocrinology, Samarkand State Medical University)
Asliddinova Sevara (student of medical course 410 group, Samarkand State Medical University)
Qodirova Feruza (student of medical course 410 group, Samarkand State Medical University)
Valijonova To`maris (student of medical course 410 group, Samarkand State Medical University)

JMGCB
Vol. 1 No. 2 (2024): Journal of Medical Genetics and Clinical Biology

Diabetic neuroosteoarthropathy (DNOA, Charcot foot) is a relatively rare complication of diabetes mellitus (DM), which can lead not only to impaired support function of the lower limb in such patients, but also to high amputation. DNOAP is characterized by persistent aseptic inflammation of the bone structures of the foot, which creates significant difficulties in planning treatment measures[1,2,3,4]. In the medical literature, there is data demonstrating the role of individual cytokines and neurohumoral factors in the prolongation of the inflammatory process in diabetes, however, studies identifying significant markers Aseptic inflammation with DNOAP is currently extremely rare[5,6,7].