Quagga: Jurnal Pendidikan dan Biologi
Vol 16 No 1 (2024): QUAGGA : Jurnal Pendidikan dan Biologi

Effectiveness of Ethanol Gel and Essential Oil of Kencur Rhizome (Kaempferia galanga L.) base Karbopol against Propionibacterium acnes

Rahayu Samalo (Mahasiswa)
Tri Gunaedi (Universitas Cenderawasih)
Dirk Y.P. Runtuboi (Universitas Cenderawasih)



Article Info

Publish Date
01 Jan 2024

Abstract

Kencur rhizome (Kaempferia galanga L.) is an aromatic herbal plant as antibacterial and anti-inflammatory. This study aims to determine the physical quality and effectiveness of gel preparations of ethanol extract and essential oil of kencur rhizome based on carbopol inhibiting Propionibacterium acnes bacteria. This study used a Randomized Block Design (RAL) with 2 different treatments of 5 levels each, namely ethanol extract gel treatment and essential oil extract gel with concentrations of 10%, 20%, 30%, 40% and 50%. The results of the gel formulation of extracts and essential oils based on carbopol showed pH, texture, spreadability and adhesiveness according to the quality standards of topical preparations. The antibacterial inhibition of the gel was moderate at 50% extract concentration (11.41 mm); and 50% essential oil (9.04 mm). Positive control treatment inhibited growth by 15.84 mm while negative control showed no response. The extract gel and essential oil of galangal rhizome had a significant effect but were less effective in inhibiting P. acnes bacteria. Adding the maximum concentration of extract and essential oil can optimize acne healing.

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Journal Info

Abbrev

quagga

Publisher

Subject

Biochemistry, Genetics & Molecular Biology Education Immunology & microbiology

Description

Quagga: Jurnal Pendidikan dan Biologi (Journal of Education and Biology) (p-ISSN 1907-3089; e-ISSN 2615-5869) is a journal managed by the Biological Education Study Program, Faculty of Teachers Training and Education Universitas Kuningan (FKIP UNIKU). This journal is issued twice a year (January and ...