Bioedukasi: Jurnal Pendidikan Biologi
Vol 3, No 2 (2012): Nopember 2012

AKTIVITAS SITOTOKSIK SENYAWA Α-TERPINEOL PADA CELL LINE KANKER LEHER RAHIM (SEL HeLa) SEBAGAI SUMBER BELAJAR BIOLOGI MATERI POKOK BIOLOGI SEL

Noor, Rasuane ( Pendidikan Biologi)



Article Info

Publish Date
01 Nov 2012

Abstract

α-terpineol is a compound of the class of  terpenoid  alcohols  derived  from natural  materials, α-terpineol can be synthesized from  α-pinene  from  turpentin content of extracts derived  from  the sap of  pine  trees  (Pinus merkusii). α-terpineol has been reported as a natural compound that has potential as anticancer agent. Objectives of research:  In general, to assess the activity of α- terpineol  compounds  against  HeLa  cells  and  the   possible  mechanism,  whereas  specifically  assessing  cytotoxic  activity. Methods: This was a quasi-experimental study using post-test only with non-equivalent control group design.  This study was conducted on HeLa cells by administering α-terpineol. Observations  cytotoxic   activity assay was performed using MTT assay method. Results: α -terpineol was cytotoxic against HeLa cells with IC50 of 12,46 μg/mL, therefore this compound was a potential anticancer   Kata kunci :  α-terpineol, sitotoksik, HeLa, kanker leher rahim 

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Journal Info

Abbrev

BIOEDUKASI

Publisher

Subject

Biochemistry, Genetics & Molecular Biology Education

Description

Bioedukasi journal contains scientific articles in the form of research, the study of literature, ideas, application of theory, critical analysis study, and studies to the Islamization of science education in the field of Biology. Bioedukasi Journal is published two times a year, the period from ...