Bali Dermatology Venereology and Aesthetic Journal
BDVJ - Vol. 1 No. 2 (December 2018)

The positive correlation between psoriasis vulgaris severity degree with HbA1C level

Made Swastika Adiguna (Dermatology and Venereology Departement, Faculty of Medicine, Udayana University, Sanglah General Hospital Denpasar, Bali-Indonesia)
Made Wardhana (Dermatology and Venereology Departement, Faculty of Medicine, Udayana University, Sanglah General Hospital Denpasar, Bali-Indonesia)
Fresa Nathania Rahardjo (Post-graduate in Dermatology and Venereology, Faculty of Medicine, Udayana University, Sanglah General Hospital Denpasar, Bali-Indonesia)



Article Info

Publish Date
08 Dec 2018

Abstract

Introduction: Psoriasis is a skin abnormality based on chronic inflammation immune-mediated. Insulin resistance and psoriasis seem to have a connection, but it has not been explained clearly. HbA1c describe the glucose concentration and demonstrate the insulin resistance condition indirectly. Objective: This study aims to understand the correlation between psoriasis vulgaris severity degree with HbA1c. Material and methods: This study was using a cross sectional method. Psoriasis vulgaris diagnosed clinically and assessed with the PASI score. The HbA1c level examination done by drawing venous blood then analyzed with chromatography method. Samples were selected by using inclusion and exclusion criteria and a consecutive sampling method. Results: Total 51 subjects (33 subjects with psoriasis vulgaris and 18 subjects without psoriasis vulgaris) were included in this study. Mostly (57.6%) of the subject was mild, 24.2% moderate, and 18.2% severe psoriasis. HbA1c level of psoriasis vulgaris subjects is significantly higher than non-psoriasis vulgaris subjects (p=0.019, PR=6.545). Correlation between severity degree and HbA1c level found in positive course significantly with moderate strength of correlation (r = 0.580, p<0.001). Conclusion: HbA1c level on psoriasis vulgaris subjects are higher than non-psoriasis vulgaris. Psoriasis vulgaris severity degree positively correlated with HbA1c.

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Journal Info

Abbrev

balidv

Publisher

Subject

Biochemistry, Genetics & Molecular Biology Health Professions Immunology & microbiology Medicine & Pharmacology Public Health

Description

Bali Dermatology Venereology and Aesthetic Journal is an open access; peer-reviewed journal aiming to communicate high-quality research articles, reviews, and general articles in the Dermatology, Venereology and Aesthetic field. The Journal aims to bridge and integrate the intellectual, ...