Jurnal EduHealth
Vol. 15 No. 01 (2024): Jurnal eduHealt, Edition January - March, 2024

Comparison of the effectiveness of using captopril and valsartan in thypertension patients with kidney failure at Citra Husada hospital

Anisa Agustina (Pharmacy Undergraduate Of Study Program)
Shinta Mayasari (Departemen Of Community And Clinical Pharmacy, Universitas Dr. Soebandi Jember, East Jawa, Indonesia)
Nafisah Isnawati (Departemen Of Community And Clinical Pharmacy, Universitas Dr. Soebandi Jember, East Jawa, Indonesia)



Article Info

Publish Date
24 Jan 2024

Abstract

Renal failure was a clinical condition characterized by irreversible decline in kidney function. Renal failure was divided into chronic and acute renal failure. Hypertension was a major factor triggering the occurrence of kidney disease and kidney failure. Data released by WHO shows that 50% of people with kidney failure, both acute and chronic, reach 50%. Based on Riskesdas, in 2018 the prevalence of chronic kidney failure in Indonesia was 0.38%. East Java Province was 0.3%, while the highest prevalence based on age was 65-74 years old at 8.23%. Effectiveness could provide information about how much a drug could achieve the desired effect in clinical practice. The purpose of this study was to compare the effectiveness of used captopril and valsartan in hypertensive patients with kidney failure at hospital. Methods: This research uses a numerical comparative analytical research type with an observational and cross-sectional design. The research was conducted at. Citra Husada Hospital in March-April 2023, using patient medical record data sources, and a sample of 64 patients. Data sources were analyzed using the Chi square test. Data is displayed in frequency and percentage form. Results: The results of this study showed that the average valued of blood pressure before administration of captopril was 183. 65 mmhg/99. The average value of blood pressure after administration of captopril was 171. 00 mmhg/91. 778 mmhg. The average value of blood pressure before administration of valsartan was 165. 87 mmhg/92. 81 mmhg. The average value of blood pressure after administration of valsartan was 151. 15 mmhg / 81. 09 mmhg. From the results of the studies, it was found that there was no difference between the comparison of the effectiveness of used captopril and valsartan in hypertensive patients with kidney failure at hospital. Conclusion: The conclusion of this study shows that there was no comparison of the effectiveness of used captopril and valsartan in hypertensive patients with kidney failure, both of which had the same effectiveness in lowering blood pressure

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Journal Info

Abbrev

healt

Publisher

Subject

Health Professions Public Health Veterinary

Description

The EduHealt journal contains articles based on research results or equivalent in the health field. The research includes research related to the community environment as well as in the general public. Articles published in this journal have never been published/published by other ...