JOSSAE (Journal of Sport Science and Education)
Vol 9 No 1 (2024)

The Increase of Brain-Derived Neurotrophic Factor Expression after Moderate-Intensity Aerobic Exercise in Obese Women

Rixco Gesang Gumelar (Universitas Negeri Malang)
Sugiharto Sugiharto (Universitas Negeri Malang)
Desiana Merawati (Universitas Negeri Malang)
Agnieszka Magdalena Nowak (Jozef Pilsudski University of Physical Education in Warsaw)
Adi Pranoto (Universitas Airlangga)



Article Info

Publish Date
31 May 2024

Abstract

Obesity is closely related to a decrease in brain-derived neurotrophic factor (BDNF) expression, which will pose a risk for metabolic disorders. Therefore, this study aims to prove the effect of moderate-intensity aerobic exercise on increasing BDNF expression in obese women. A total of sixteen obese women were selected based on predetermined criteria and were divided into 2 groups, namely the aerobic exercise group (AE) and the control group (CN). Aerobic exercise was carried out by running on a treadmill at moderate intensity (60-70 HRmax) for 40 minutes/session with a frequency of 5x/week for 2 weeks. Blood samples were taken twice before and after exercise intervention to see BDNF expression using the Enzyme-Linked Immunosorbent Assay (ELISA-kit) method. The results of the analysis showed differences in increase between the control group (1816.66 ± 689.48 vs. 1822.86 ± 467.87 pg/mL; p = 0.974) and the intervention group (2173.81 ± 705.89 vs. 3635.01 ± 699.71 pg/mL; p = 0.013). This shows that moderate-intensity aerobic exercise carried out for 2 weeks has proven effective in increasing BDNF expression in obese women.

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Journal Info

Abbrev

jossae

Publisher

Subject

Other

Description

Sport Science Physical Education Sport Coaching Sport Psychology Strength and conditioning Sport ...