Jurnal Sains, Teknologi dan Kesehatan
Vol. 3 No. 2 (2024): Jurnal Sains, Teknologi dan Kesehatan, April 2024

Pengaruh Pemberian Ekstrak Bengkuang (Pachyrhizus Erosus) sebagai Antioksidan terhadap Kadar Kolesteroltinggi pada Mencit (Mus Musculus)

Fardani, Roushandy Asri (Unknown)
Mentari, Ika Nurfajri (Unknown)
Fitria, Eka (Unknown)



Article Info

Publish Date
30 Apr 2024

Abstract

High cholesterol levels in the blood are a serious problem because they are a risk factor for various non-communicable diseases such as heart disease, stroke and diabetes mellitus. Empirically, the secondary metabolic contents of jicama such as saponins& flavonoids have their respective properties. Saponin functions to bind cholesterol with bile acids so that it can reduce cholesterol levels. The results of the antioxidant activity test, the IC50 value of jicama extract is 115.20 mg/mL, which indicates that the antioxidant activity of jicama extract is classified as a moderate antioxidant. The results of measuring cholesterol levels after treatment showed that there was a decrease in cholesterol levels after giving jicama extract treatment in each group, seen in treatment 1 (P1) at 113.4 with a difference of 2.6 from cholesterol before administration, treatment 2 (P2) at 110.8 with a difference of 4.6 of cholesterol before administration, treatment 3 (P3) was 110.6 with a difference of 7.6 from cholesterol before administration of jicama extract, positive control (K+) was 108.4 with a difference of 30.2 from cholesterol before administration, negative control (K-) was 122.6 with a difference of 0.2 antioxidants from purple cabbage, namely 115.20 μg/mL. The antioxidant activity of purple cabbage is in the very strong category and vitamin C is in the very strong category.

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Journal Info

Abbrev

saintekes

Publisher

Subject

Civil Engineering, Building, Construction & Architecture Computer Science & IT Electrical & Electronics Engineering Industrial & Manufacturing Engineering Materials Science & Nanotechnology

Description

SAINTEKES : Jurnal Sains, Teknologi dan Kesehatan is a forum for academics, researchers and practitioners to publish original works that have never been published before. The focus and scope of topics published in this journal include: Science, Technology, and ...