The aim of this research is to examine the relationship between cash ratio, debt to equity ratio, and profitability. This research combines quantitative techniques with an associative descriptive approach. Over a period of five years, samples of financial report data from eleven companies were collected using a census approach. The Chow and Hausman tests are used in selecting the panel data regression model. The data processing tool used is called E-Views 12. The selected model is used to confirm conventional wisdom. This research involves model selection, panel data regression analysis, coefficient of determination, and testing its significance using t and F tests. The results of the research show that the Debt to Equity Ratio (DER) and Cash Ratio have a significant influence on profitability. It was determined that a random effects model was appropriate. The debt to equity ratio (DER) and cash ratio both have a positive effect on profitability, based on the findings of the significance test. However, the impact on profitability is slightly higher
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