The Indonesian Journal of General Medicine
Vol. 1 No. 2 (2024): The Indonesian Journal of General Medicine

The Correlation Between Probiotics and Gastroesophageal Reflux Disease (GERD): A Comprehensive Review

Hendrik (Unknown)
Suryadi (Unknown)



Article Info

Publish Date
01 Jun 2024

Abstract

Background: It has been demonstrated that probiotics, or live microorganisms, can lessen GERD symptoms and enhance gut health. They can help with bowel movements and abdominal pain, which helps with managing GI tract disorders in general and irritable bowel syndrome in particular (IBS). Methods: We conducted a search without sample size restrictions in the PubMed and Web of Science databases to find prospective studies on dyspepsia, heartburn, regurgitation, and GERD. The analysis comprised a total of ten published prospective studies. Result: Studies have reported that probiotics can alleviate GERD symptoms, including reflux. These studies have shown that probiotics can reduce regurgitation, improve reflux or heartburn, alleviate dyspepsia, and improve other upper gastrointestinal symptoms like nausea, abdominal pain, and gas-related symptoms. Conclusion: In the general adult population, probiotics have been shown to lessen upper gastrointestinal symptoms of GERD, especially those derived from Lactobacillus and Bifidobacterium. By interacting with stomach mucosal receptors, they modify the immune response and antagonistic activity towards potential pathogens, accelerating gastric emptying.

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Journal Info

Abbrev

ijgm

Publisher

Subject

Dentistry Health Professions Medicine & Pharmacology Public Health Veterinary

Description

ims: The Indonesian Journal of General Medicine aims to advance the field of medicine by disseminating high-quality research findings that are accessible to a broad audience of healthcare professionals, researchers, and policymakers. The journal is committed to supporting the development of medical ...