Journal of Mathematics: Theory and Applications
Vol 6 No 1 (2024): Volume 6, Nomor 1, 2024

Global Sensitivity Analysis of A Rabies Epidemic Model involving Dog Vaccination and Dog Population Management

Nur, Wahyudin (Unknown)
Darmawati (Unknown)



Article Info

Publish Date
06 Apr 2024

Abstract

Rabies is a zoonotic disease which is spread by animals mostly carnivores. Rabies regards as tropic disease. In this article, we construct a mathematical model for rabies involving dog vaccination and dog population management. The model has two equilibrium points, namely rabies-free equilibrium point and endemic equilibrium point. We determine the effective reproduction ratio using next generation matrix. Our dynamical analysis shows that rabies-free equilibrium point is conditionally stable. A global sensitivity analysis is performed to investigate which intervention is the most crucial among the two interventions considered in the model. We use Latin hypercube sampling method to generate parameter space. To investigate the parameter sensitivity, we calculate the partial rank correlation coefficient. We provide numerical experimental results related to stability and global sensitivity analysis. Our results show that the effective reproduction ratio is more sensitive to dog population management than vaccination intervention. This suggests that dog population management intervention, such as sterilization and monitoring of dog movements significantly reduces the effective reproduction ratio compared to vaccination programs. In addition, the number of infectious dogs has a strong correlation with dog culling actions.

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Journal Info

Abbrev

Mathematics

Publisher

Subject

Mathematics

Description

JOMTA Journal of Mathematics Theory and applications is a national journal intended as a communication forum for mathematicians and other scientists from many practitioners who use mathematics in the research. JOMTA Journal of Mathematics Theory and applications disseminates new research results in ...