JMGCB
Vol. 1 No. 2 (2024): Journal of Medical Genetics and Clinical Biology

Estimated Glycation End Products and Oxidative Status in Renal Failure Patients

Salam Khalid Mutlag (a:1:{s:5:"en_US"
s:60:"Ministry of Education, Directorate of Kirkuk Education, Iraq"
})

Mohanad Hammo Mukhlif1 (Ministry of Education, Directorate of Kirkuk Education, Iraq)



Article Info

Publish Date
14 Mar 2024

Abstract

The present study conducted to assess the Glycation end products and oxidative status of in patients with renal failure. 100 patients that have had CKD for less than 2 years have been diagnosed by a doctor. A control group of 40 stable individuals was selected. From October 2021 to February 2022, patients were confirmed to be sick with chronic renal disease at Azadi Teaching Hospital and Al-Jumhuri Hospital. ‎the results showed that the largest age group of patients was > 60 years with percent (39%). Body Mass Index (BMI) of patients was 18.5-24.9 kg with percent (52%). Residential Area of patients was urban with percent (83%). Smoking Status of patients was non-smoking with percent (68%). The current outcomes demonstrated a reduction in the concentration of total protein that is significant (P<0.05), albumin and globulin in patients compare with healthy volunteers. On the other hand, the results show a significant (P<0.05) elevated in levels of carbonyl and amino group, while decreased in thiol levels in patients compare with healthy volunteers. Otherwise, the Glycation level shows significant (P<0.05) elevated in in patients compare with healthy volunteers. Its concluded that the CKD lead to elevated Glycation level and changes in oxidative status.

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Journal Info

Abbrev

JMGCB

Publisher

Subject

Biochemistry, Genetics & Molecular Biology Medicine & Pharmacology

Description

The European Journal of Medical Genetics and Clinical Biology is a peer-reviewed journal that publishes articles in English on various aspects of human and medical genetics, the genetics of experimental models, and developmental anomalies. Original clinical and experimental research articles, short ...