BIOCHEMISTRY OF DNA: A STUDY OF CHEMICAL EFFECTS ON GENE EXPRESSION

Mina Hussein Ubead (Wasit university, College of scince, Biology)
Haneen Hussein Rahim Mahdi (Al-Qadisiyah University, College of Science, Department of biology)
Haneen Abbass Majeed Abbass (University of Baghdad, College of Science, Department of biology)
Eman Maher Khalil Faisal (Al_Mustansiriyah University, College of science, Department of chemistry)
NoorAl-Huda Maher Khalil Faisal (Karbala University, College of science, Department of biology)
Athraa Bassem Mohammed nayel (University of Thi Qar, College of Science, Department of biology)

JMGCB
Vol. 1 No. 8 (2024): Journal of Medical Genetics and Clinical Biology

The study of DNA biochemistry is pivotal to understanding the molecular mechanisms that govern gene expression. This research delves into the intricate chemical processes that influence DNA structure, function, and regulation. By examining the interplay between DNA and various chemical agents, such as methylating and acetylating compounds, we explore how these modifications impact gene expression. Our investigation encompasses both endogenous factors, like natural metabolic byproducts, and exogenous influences, including environmental toxins and pharmaceuticals. Through a combination of advanced biochemical techniques and computational modeling, we aim to elucidate the pathways through which chemical modifications alter gene expression patterns. This comprehensive analysis not only enhances our understanding of fundamental genetic processes but also provides insights into the development of novel therapeutic strategies for genetic and epigenetic disorders. The findings underscore the significance of chemical interactions in gene regulation and highlight potential avenues for targeted interventions in disease treatment and prevention.