Antibacterial activity of ten medicinal plants obtained from some selected villages in the states of Kedah and Penang, Malaysia

Othman Abd Samah (Department of Biomedical Science, Faculty of Science, International Islamic University Malaysia Bandar Indera Mahkota, 25200 Kuantan, Malaysia.)
Nurdiana Zainol Abidin (Department of Biomedical Science, Faculty of Science, International Islamic University Malaysia Bandar Indera Mahkota, 25200 Kuantan, Malaysia.)

INDONESIAN JOURNAL OF PHARMACY
Vol 20 No 2, 2009

The antimicrobial activities of ten plant extracts showed some degree of variation among Gram positive and Gram negative bacteria. Nineteen crude plant extracts were active against Gram positive bacteria as compared to only 9 against Gram negative bacteria. The most resistant bacteria was K. pneumoniae K6 which showed no sign of susceptibility towards any of the plant extracts. This might be due to the presence of ß-lactamase, which had been reported recently. S. epidermidis* showed susceptibility towards all plants except for M. citrifolia L. The highest zone of inhibition was 14.67 mm which was found in P. guajava extracts against S. epidermidis and this is closely followed by M. indica (at 13.67 mm ) against the same bacteria. Among all the plants which have been studied only M. citrifolia L. extract did not show any sign of antimicrobial activity. The result showed that means of inhibition zones between each plant extract were significantly different.Key words: Antibacterial; Gram positive; Gram negative; medicinal plants.