INDONESIAN JOURNAL OF PHARMACY
Vol 12 No 4, 2001

PHYTOCHEMICAL SCREENING, TOXICITY AND ANTI-BACTERIAL ASSAY FROM STEM-BARK EXTRACTS OF Garcinia celebica and G. tetandra

Yuliasri Jamal (Research Center For Biology - Cibinong Science Center (CSC) JL. Raya Jakarta - Bogor Km.46 Cibinong 16911 Bogor - Indonesia Phone:+62(0)21-87907604/87907636 Fax : +62(0)21-87907612)
Praptiwi . (Research Center For Biology - Cibinong Science Center (CSC) JL. Raya Jakarta - Bogor Km.46 Cibinong 16911 Bogor - Indonesia Phone:+62(0)21-87907604/87907636 Fax : +62(0)21-87907612)
Andria Agusta (Research Center For Biology - Cibinong Science Center (CSC) JL. Raya Jakarta - Bogor Km.46 Cibinong 16911 Bogor - Indonesia Phone:+62(0)21-87907604/87907636 Fax : +62(0)21-87907612)



Article Info

Publish Date
01 Oct 2005

Abstract

Garcinia is suggested to have multi benefit in curing various diseases, some have edible fruit and edible oil. This experiment was a preliminary analysis, including phytochemistry screening, toxicity and antibacterial testing of stem-bark G. celebica and G. tetandra extracts. Ether, ethanol and water extracts of both Garcinia contained 19 different chemical components. Hexane, methanol and water extracts of stem-bark of both Garcinia extracts were found to have toxicological effect on Artemisia salina larva, G. celebica water extract had highest LC50 . Dichloromethane-methanol 1:1 extract of G. celebica inhibited the growth of Gram positive and Gram negative bacteria , while the extract of G. tetandra could only inhibit the growth of Gram negative bacterium. Comparing with erythromycin and novobiosin antibiotics, the inhibiton growth activity of the two Garcinia extracts were lower than those of the antibiotics. Key words: Garcinia, phytochemical screening, toxicological effect, anti-bactery

Copyrights © 2001






Journal Info

Abbrev

3

Publisher

Subject

Medicine & Pharmacology

Description

Indonesian Journal of Pharmacy (ISSN-e: 2338-9486, ISSN-p: 2338-9427), formerly Majalah Farmasi Indonesia (ISSN: 0126-1037). The journal had been established in 1972, and online publication was begun in 2008. Since 2012, the journal has been published in English by Faculty of Pharmacy Universitas ...