INDONESIAN JOURNAL OF PHARMACY
Vol 16 No 3, 2005

Antioxidant potency of ethanolic extract of Kemuning leaves (Murraya paniculata (L) Jack ) in vitro

Rohman, Abdul (Laboratory of Chemistry, Department of Pharmaceutical Chemistry, Faculty of Pharmacy, Gadjah Mada University, Yogyakarta Indonesia)
Riyanto, Sugeng (Laboratory of Chemistry, Department of Pharmaceutical Chemistry, Faculty of Pharmacy, Gadjah Mada University, Yogyakarta Indonesia)



Article Info

Publish Date
01 Jul 2005

Abstract

Antioxidants are the compounds capable to inhibit free radical reactions in the human body. This research was aimed to identify the antioxidant potency of ethanolic extract of kemuning leaves in vitro by using linoleic-thiocyanate and DPPH (2,2-diphenyl-1-picryl hydrazyl) methods. The ethanolic extract of kemuning leaves was diluted in various concentrations i.e. 1%,5% and 10% and determined their antioxidant potencies. By using linoleic-thiocyanate method, the result suggested, that ethanolic extract of 1%; 5 % and 10 % showed antioxidant potencies and had significant different absorbances (P < 0,05). The antioxidant potencies of ethanolic extract with different concentrations were also measured by DPPH method and the result showed that ethanolic extracts of kemuning leaves revealed the antioxidant activity with the IC50 of 126,17 µg/ml, 15 times lower than that of vitamin E (IC of 8,27 µg/ml). The antioxidant activity of kemuning leaves probably due to the flavonoid content.

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Journal Info

Abbrev

3

Publisher

Subject

Medicine & Pharmacology

Description

Indonesian Journal of Pharmacy (ISSN-e: 2338-9486, ISSN-p: 2338-9427), formerly Majalah Farmasi Indonesia (ISSN: 0126-1037). The journal had been established in 1972, and online publication was begun in 2008. Since 2012, the journal has been published in English by Faculty of Pharmacy Universitas ...