A study of wound healing process in post total laryngectomy patients: Serial case reports

Srifia Wardianti (Department of Ear, Nose, Throat, Head and Neck Surgery, Faculty of Medicine, Universitas Syiah Kuala, Banda Aceh, Indonesia Department of Ear, Nose, Throat, Head and Neck Surgery, Dr Zainoel Abidin General Hospital, Banda Aceh, Indonesia)
Iskandar Zulkarnain (Department of Ear, Nose, Throat, Head and Neck Surgery, Faculty of Medicine, Universitas Syiah Kuala, Banda Aceh, Indonesia Department of Ear, Nose, Throat, Head and Neck Surgery, Dr Zainoel Abidin General Hospital, Banda Aceh, Indonesia)
Benny Kurnia (Department of Ear, Nose, Throat, Head and Neck Surgery, Faculty of Medicine, Universitas Syiah Kuala, Banda Aceh, Indonesia Department of Ear, Nose, Throat, Head and Neck Surgery, Dr Zainoel Abidin General Hospital, Banda Aceh, Indonesia)
Lily Setiani (Department of Ear, Nose, Throat, Head and Neck Surgery, Faculty of Medicine, Universitas Syiah Kuala, Banda Aceh, Indonesia Department of Ear, Nose, Throat, Head and Neck Surgery, Dr Zainoel Abidin General Hospital, Banda Aceh, Indonesia)
Fadhlia Fadhlia (Department of Ear, Nose, Throat, Head and Neck Surgery, Faculty of Medicine, Universitas Syiah Kuala, Banda Aceh, Indonesia Department of Ear, Nose, Throat, Head and Neck Surgery, Dr Zainoel Abidin General Hospital, Banda Aceh, Indonesia)
Safarianti Safarianti (Department of Parasitology, Medical Faculty, Universitas Syiah Kuala, Banda Aceh, Indonesia)

Trends in Infection and Global Health
Vol 2, No 2 (2022): December 2022

Laryngeal carcinoma is a malignancy on larynx that may occur in glottic, supraglottic and subglottic. Larynx plays role in coordination of upper aerodigestive tract such as breathing, verbal and swallowing. This reported as the third most common malignancy in the ENT-HN department. Total laryngectomy is a procedure that performed on T3 and T4 lesions. The most common complication is prolonged of the wound healing process. The process is very complex  consist of four overlapping phases that involve multifactorial divided into local and systemic factors. Local factors include oxygenation and infection, while systemic factors are age, gender, psychological stress, nutrition, chronic disease and immunocompromise conditions. In this case, seven patients underwent total laryngectomy and contributing factors of wound healing process were observed in each patient until 14th postoperative day. Some of important factors might contributed to the wound healing process in some patients such as psychological stress, nutrition and chronic disease such as diabetes mellitus and hypertension.