Biomedical Journal of Indonesia
Vol. 10 No. 2 (2024): Vol 10, No 2, 2024

The Impact of Sambiloto Extract (Andrographis paniculata) as a Potential Antidiabetic Treatment

Clara Alverina (Postgraduate of Medical Doctor, Faculty of Medicine, Universitas Sriwijaya, Palembang, Indonesia)
Nita Parisa (Department of Pharmacology, Faculty of Medicine, Universitas Sriwijaya, Palembang, Indonesia)
Rio Dwi Arliansyah (Postgraduate of Medical Doctor, Faculty of Medicine, Universitas Sriwijaya, Palembang, Indonesia)
Nia Savitri Tamzil (Department of Pharmacology, Faculty of Medicine, Universitas Sriwijaya, Palembang, Indonesia)



Article Info

Publish Date
04 Jun 2024

Abstract

Diabetes mellitus (DM) is a metabolic disease caused by an inappropriate increase in blood glucose levels. The development of traditional medicines, including extracts, fractions, and isolates from plants, remains highly intriguing and challenging. Andrographis paniculata is a one of medicinal plants with a long history of use in Asia for the treatment of various ailments. Andrographolide, a bioactive compound found in A. paniculata, has been extensively studied for its medicinal benefits, specifically its antidiabetic effects. This study employs a literature review approach to investigate the effect of Sambiloto extract (Andrographis paniculata) as an antidiabetic medication using Google Scholar, Science Direct, and PubMed databases. The publication year range for the literature data sources is from 2020 to 2024. Based on the conducted searches, three reference journals are included in this study. Andrographolide, the active compound contained in Sambiloto, may act as an antidiabetic medication through various mechanisms, thus representing a potential treatment for diabetes mellitus.

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Journal Info

Abbrev

bji

Publisher

Subject

Biochemistry, Genetics & Molecular Biology Medicine & Pharmacology

Description

Biomedical Journal of Indonesia is an open access, peer-reviewed journal that focus on basic medical sciences, emphasizing on providing the molecular studies of biomedical problems and molecular mechanisms to integrate researches in all aspects of human health. BJI is dedicated to publishing ...