Bandung Conference Series: Pharmacy
Vol. 3 No. 2 (2023): Bandung Conference Series: Pharmacy

UJI AKTIVITAS ANTIJAMUR EKSTRAK ETANOL KULIT BUAH PETAI (PARKIA SPECIOSA HASSK.) TERHADAP PERTUMBUHAN CANDIDA ALBICANS DAN MICROSPORUM GYPSEUM

Luzhny Azzahra (Pharmacy)
Lanny Mulqie (Prodi Farmasi, Fakultas Matematika dan Ilmu Pengetahuan Alam)
Ratu Choesrina (Prodi Farmasi, Fakultas Matematika dan Ilmu Pengetahuan Alam)



Article Info

Publish Date
20 Jan 2024

Abstract

Abstract. Petai plant (Parkia speciosa Hassk.) is known to contain metabolite compounds that can be developed to treat several diseases, one of which is antifungal. This study aims to determine the antifungal activity of ethanol extract of petai fruit peel (Parkia speciosa Hassk.) against the growth of Candida albicans and Microsporum gypseum, and determine the value of the inhibition zone in ethanol extract of petai fruit peel (Parkia speciosa Hassk.) against the growth of Candida albicans and Microsporum gypseum. The method used was agar diffusion (wells). The concentrations of the extracts tested were 1, 5, 10, 15, and 20%. The positive control used was ketoconazole 2% and the negative control was DMSO. The results of the calculation of the average zone of inhibition of ethanol extract of petai fruit peel against Candida albicans at concentrations of 1, 5, 10, 15, and 20% were 13,9; 15,5; 17,6; 18,9; and 20,3 mm, respectively. The results of the calculation of the inhibition zone of ethanol extract of petai fruit peel against Microsporum gypseum at concentrations of 1, 5, 10, 15, and 20% were 17,5; 19,8; 18,6; 23,7; and 26,6 mm, respectively. The results showed that ethanol extract of petai fruit peel (Parkia speciosa Hassk.) has antifungal activity with the formation of an inhibition zone around the wells. Abstrak. Tanaman petai (Parkia speciosa Hassk.) diketahui memiliki kandungan senyawa metabolit yang dapat dikembangkan untuk mengobati beberapa penyakit, salah satunya antijamur. Penelitian ini bertujuan untuk mengetahui aktivitas antijamur ekstrak etanol kulit buah petai (Parkia speciosa Hassk.) terhadap pertumbuhan Candida albicans dan Microsporum gypseum, serta mengetahui nilai zona hambat pada ekstrak etanol kulit buah petai (Parkia speciosa Hassk.) terhadap pertumbuhan Candida albicans dan Microsporum gypseum. Metode yang digunakan adalah difusi agar (sumuran). Konsentrasi ekstrak yang diuji yaitu 1, 5, 10, 15, dan 20%. Kontrol positif yang digunakan yaitu ketokonazol 2% dan kontrol negatif yaitu DMSO. Hasil perhitungan rata-rata zona hambat ekstrak etanol kulit buah petai terhadap Candida albicans pada konsentrasi 1, 5, 10, 15, dan 20% berturut-turut sebesar 13,9; 15,5; 17,6; 18,9; dan 20,3 mm. Hasil perhitungan zona hambat ekstrak etanol kulit buah petai terhadap Microsporum gypseum pada konsentrasi 1, 5, 10, 15, dan 20% berturut-turut sebesar 17,5; 19,8; 18,6; 23,7; dan 26,6 mm. Dari hasil penelitian menunjukkan ekstrak etanol kulit buah petai (Parkia speciosa Hassk.) memiliki aktivitas antijamur dengan terbentuknya zona hambat disekitar sumuran.

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Journal Info

Abbrev

BCSP

Publisher

Subject

Chemistry Medicine & Pharmacology Public Health

Description

Bandung Conference Series: Pharmacy (BCSP) menerbitkan artikel penelitian akademik tentang kajian teoritis dan terapan serta berfokus pada Farmasi dengan ruang lingkup Airlock system Kanker, Alcohol, Antelmintik, Antigastritis drugs, Antioksidan, Artemia franciscana, Ascaris suum, Cacing babi ...