Teaching materials are important components in learning, so they need more attention. This study aimed to determine the validity and response of the target audience to a STEM-based chemistry e-module on reaction rate. The research used the ADDIE development model, which consists of five stages: Analyze, Design, Develop, Implement, and Evaluate. However, this research was limited to the implementation stage through trials with a small group. The research instruments used were interview guidelines, student needs questionnaire sheets, validation sheets, and teacher and student response questionnaire sheets. The subjects of this study were 3 expert lecturers, 2 expert chemistry teachers, and 30 students of class XII IPA at SMA Negeri 2 Sentajo Raya. The results showed that the STEM-based chemistry e-module on reaction rate material was feasible to use with a validity value of 89.6% (very feasible criteria). Based on the responses of the target audience, it can also be concluded that the e-module is feasible to use with a teacher response percentage of 92% and students 88%. This means that e-modules are feasible to use as teaching materials on reaction rate materials at SMAN 2 Sentajo Raya. Therefore, to apply and implement this e-module to other schools, further studies are needed.
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