ad-Dawaa : Journal of Pharmaceutical Sciences
Vol. 6 No. 2 (2023)

Breaking Boundaries: A Comparative Analysis of Weak vs. Strong Bases in Eugenol Isolation from Syzygium aromaticum (L.) Merr. & LM Perry

Handayani, Dwi (Unknown)
Sitindaon, Rina SE (Unknown)
Hidayati, Nurul (Unknown)
Setiawansyah, Arif (Unknown)



Article Info

Publish Date
31 Dec 2023

Abstract

Eugenol, a phenolic compound classified within the phenylpropanoid group, stands out as a key constituent of clove oil, boasting a myriad of biological activities. Its isolation typically involves the utilization of an alkaline solution, yet the choice of alkaline agent significantly impacts the yield of eugenol. This study delves into the impact of various alkaline solutions on the isolated eugenol content from Syzygium aromaticum essential oil, leveraging its acidic properties to form a soluble eugenol salt in an aqueous medium. Employing alkaline solutions with a concentration of 1 N, including both strong bases (such as KOH, NaOH, and Ba(OH)₂) and weak bases (like Ni(OH)₂, Al(OH)₃, and Zn(OH)₂), we scrutinized the diverse outcomes on eugenol content. Results revealed that KOH yielded the highest eugenol content at 96.91%, while Zn(OH)₂ displayed the lowest at 20.99%. Nevertheless, the potential of weak alkaline solutions in the eugenol isolation process from Syzygium aromaticum essential oil remains noteworthy. Future endeavors should focus on optimizing the ideal concentration of weak alkaline solutions for this purpose.

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Journal Info

Abbrev

addawaa

Publisher

Subject

Biochemistry, Genetics & Molecular Biology Chemistry Immunology & microbiology Materials Science & Nanotechnology Medicine & Pharmacology

Description

ad-Dawaa Journal of Pharmaceutical Sciences (DJPS) merupakan jurnal yang terbit dua kali dalam setahun, yaitu setiap Juni dan Desember. Jurnal ini fokus pada seluruh bidang terkait ilmu farmasi, termasuk biologi farmasi, farmakokimia, farmakologi, farmasi klinik dan teknologi farmasi. Jurnal ini ...