E-Jurnal Medika Udayana
Vol 13 No 2 (2024): E-Jurnal Medika Udayana

UJI PENGHAMBATAN AKTIVITAS ENZIM ALFA-GLUKOSIDASE TERHADAP DUA PRODUK JAMU KAPSUL EKSTRAK KAYU MANIS (Cinnamomum burmannii)

Febrianda, Larasati Hanifa (Unknown)
Jawi, I Made (Unknown)
Widiarthini, Ida Ayu Alit (Unknown)
Aman, I Gusti Made (Unknown)



Article Info

Publish Date
23 Feb 2024

Abstract

Cinnamon (Cinnamomim burmannii) found in the markets, comes in many forms with one of them being a type of jamu which the cinnamon dust is capsulized. The capsulized jamu is claimed to be beneficial on treating diabetes melitus. The effects of antidiabetics on some products of the capsulized jamu is suspected to work through the alpha-glucosidase enzyme inhibition activites contained in them. The aim of this research is to verify the activities of some capsulized cinnamon dust extract in jamu (C. burmannii) found in the markets on its effect to inhibit alpha-glucosidase activity and to know its IC50 value. Experiment is done by using analytic experiments using two different products (product A and product B) and by using acarbose 50mg as a positive control factor. Enzyme activity are then calculated using UV-Vis spectrophotometer on a 410 nm wavelength. The result of this research is alpha-glucosidase enzyme inhibition activity found in product A and B are 155,104 µg/mL and 6.795,893 µg/mL, wherease the acarbose as a positive control are 47,466 µg/mL. The conclusion of this research is alpha-glucosidase enzyme inhibition activity found on the products as IC50 shows that product A has a better alpha-glucosidase enzyme inhibition activity than product B. However, when compared to the acarbose as the positive control, product A has a lesser alpha glucosidase enzyme inhibition activity. Kata kunci : Cinnamomum burmannii, diabetes mellitus, alpha glucosidase inhibition.

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Journal Info

Abbrev

eum

Publisher

Subject

Health Professions Medicine & Pharmacology

Description

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