The Effects and Treatments for Usher Syndrome: A Review

Heerlie, Devita Mayanda
Margaretha, Febrina
Fugaha, Daniel Ryan
Parikesit, Arli Aditya

Indonesian Journal of Life Sciences
2024: IJLS Vol 06 No.01

Usher syndrome is defined as the rare genetic disorder that affects both vision and auditory. Although the prevalence is really low, only about 4 to 17 per 100,000 people, it is noted to cover at least 50% of deaf-blindness cases. After reviewing the molecular genetics from several papers, there are several causative genes found with the most prevalent being MYO7A, and USH2A that cause USH type 1 and 2 respectively. Furthermore, other literature has found promising treatments that may help to slow down or prevent further degeneration of the syndrome.