Alzheimer's disease is an age-related neurodegenerative disease. This disease is a major cause of dementia, which is characterized by a progressive decline in cognitive function. Beside the high number of cases, the decline in cognitive function in Alzheimer's disease also causes health problem and social problems, which is a burden for the care giver. It is important to understand the therapeutic management of Alzheimer's patients as well as the procedure for the dose titration and switching therapy to achieve maximum therapeutic effectiveness. Indications for replacement therapy are side effects/intolerance, adherence, drug interactions, dosing profile and low efficacy. Keyword: Alzheimer, dementia, management, medication
                        
                        
                        
                        
                            
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