Detection of skin cancer in its early phase is a challenge even for dermatologists. This study aims to analyze the performance of classification methods on multiclass skin cancer datasets using K-nearest neighbor (KNN) and histogram of oriented gradients (HOG). The dataset is taken publicly under the name Skin Cancer MNIST dataset: HAM10000 dataset totaling 10,015 data. The first experiment used the pixels per cell parameter of 8.8 and cells per block of 2.2 to get an accuracy of 60.58%. The second experiment used the pixels per cell parameter of 8.8 and cells per block of 2.2 to get an accuracy of 60.58%. The last experiment using the pixels per cell parameter of 8.8 and cells per block of 2.2 got the best accuracy of 61.43%.
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