Nusantara Science and Technology Proceedings
1st International Conference on Health and Medicine

The Socio-demographics and Clinical Characteristics and CD4 Profile of HIV/AIDS Patients Receiving First Line Antiretroviral Therapy at a Public Hospital in Palu

Alwiyah Mukaddas (Department of Pharmacy, FMIPA, Universitas Tadulako, Palu 94148, Central Sulawesi, Indonesia)
Ingrid Faustine (Department of Pharmacy, FMIPA, Universitas Tadulako, Palu 94148, Central Sulawesi, Indonesia)
Pupuy Astarina Pilanto (Department of Pharmacy, FMIPA, Universitas Tadulako, Palu 94148, Central Sulawesi, Indonesia)
Nurhayati Adnan (Department of Epidemiologi, FKM, Universitas Indonesia, Depok 16424, West Java, Indonesia)



Article Info

Publish Date
21 Nov 2023

Abstract

The Joint United Nations Program on HIV/AIDS (UNAIDS) set the pushful 90-90-90 target in 2015. It can be a difficult target to achieve without a comprehensive understanding of HIV epidemiology. This study aims to identify demographic and clinical characteristics and determine the difference between CD4 counts pre and post-antiretroviral (ARV) therapy in HIV patients of HIV/AIDS at a Public Hospital in Palu. A retrospective cross-sectional study of 27 HIV/AIDS patients was conducted between January 2011 and December 2015. Data were collected from medical records and electronic registries for HIV/AIDS patients. The study included 27 patients with complete data set from 230 patients, 63% productive age (25 - 44 years), 77,8% male, 85,2% were employed, 48,1% were well educated (from senior high school and equal), and 59,3% were married. The majority of patients acquired HIV through heterosexual transmission, 40,7%. At the time of the first clinic visit, 40,7% of patients had WHO stage III HIV infection. The rates of Candidiasis and TB coinfections were 22,2% and 18,5%, respectively. ZDV/3TC/NVP (74,1%) is the most commonly used antiretroviral combination. The baseline CD4+ cells count was < 350 cells/mm3 in 100% (n = 27) of patients, CD4+ median 126 cells/mm3. After Antiretroviral Therapy (ART) 6 months, two patients had a normal range CD4 500-1300 cells/mm3, CD4+ median 203 cells/mm3. There was a significant increase in CD4 count after ARV therapy (p=0,000; p<0,05). It suggests that ARV therapy can improve CD4 and immune recovery in HIV/AIDS patients.

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Journal Info

Abbrev

nuscientech

Publisher

Subject

Agriculture, Biological Sciences & Forestry Chemical Engineering, Chemistry & Bioengineering Economics, Econometrics & Finance Engineering Law, Crime, Criminology & Criminal Justice Materials Science & Nanotechnology Medicine & Pharmacology

Description

NST Proceeding supports regional research communities to globalise their findings in Science and Technology by providing an open access, online platform in line with international publishing standards and indexing scholarly conference proceedings. The current emphasis of the NST Proceeding includes ...