Jurnal Farmasi Galenika
Vol 3 No 01 (2016): JURNAL FARMASI GALENIKA

ETHANOL EXTRACT FORMULATION OF TUNJUK LANGIT RHIZOME AS TABLET BY WET GRANULATION METHOD

Fitrya A (Department of Pharmacy, Sriwijaya University, Jl. Raya Palembang-Prabumulih Km 32, Indralaya, OI, South Sumatra, Indonesia)



Article Info

Publish Date
22 Mar 2017

Abstract

Tunjuk langit rhizome (Helminthostahcys zeylanica (Linn) Hook) has been used traditionally as an anticancer and antiinflammatory agent. Previous studies have proved the potency of ethanol extract from this rhizome as an antihyperuricemic agent. In this study, the ethanol extract of the rhizome, was formulated into tablet dosage forms by a wet granulation method. Three tablet formulas with different types of disintegrant and binder were formula A (starch: PVA), formula B (Avicel®PH102: PVP), and formula C (sodium alginate: methylcellulose). Physical properties (such as weight variation, tablet diameter, thickness, friability, hardness, and disintegration time) and dissolution of tablets were evaluated. The analysis results showed that formula A produced the best physical properties and dissolution characteristics.

Copyrights © 2016






Journal Info

Abbrev

jfg

Publisher

Subject

Medicine & Pharmacology Public Health

Description

The aim of JFG is to become a media for the publication of articles on Pharmaceutical and related practice-oriented subjects in the pharmaceutical sciences and technology. The scope of the journal is Pharmaceutical sciences, its research and its application. The journal aims to cover the latest ...