Jurnal Buana Farma
Vol. 4 No. 4 (2024): Jurnal Buana Farma : Jurnal Ilmiah Farmasi

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Fikayuniar, Lia (Unknown)
Yuniarsih, Nia (Unknown)
Abriyani, Ermi (Unknown)
Ayesha, Adinda (Unknown)



Article Info

Publish Date
31 Dec 2024

Abstract

Temulawak (Curcuma xanthorrhiza Roxb) is a rhizome plant that has long been used in traditional medicine in Indonesia. The active compounds in temulawak function as antioxidants, which are essential in combating free radicals and preventing cell damage. This study aims to compare the antioxidant activity of ethanol extracts of temulawak obtained through maceration and ultrasonic extraction methods. The research method applied is pre-experimental, with testing conducted in triplicate to ensure result validity. Antioxidant activity was evaluated using the DPPH (2,2-diphenyl-1-picrylhydrazyl) method. The results show that the ethanol extract of temulawak obtained via maceration method has an IC50 value of 33.379 µg/ml. In contrast, the ultrasonic extraction method showed a lower IC50 value of 9.454 µg/ml, indicating stronger antioxidant activity. Temulawak, as an antioxidant source, has significant potential in the development of herbal products. The comparison of the two extraction methods shows that the ultrasonic method is more effective in enhancing antioxidant activity. This study emphasizes that the extraction method influences the antioxidant activity of temulawak. These results could serve as an important reference for the development of herbal-based products in the future.

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Journal Info

Abbrev

buanafarma

Publisher

Subject

Biochemistry, Genetics & Molecular Biology Chemistry Immunology & microbiology Medicine & Pharmacology

Description

The major focus of Jurnal Buana Farma is to publish articles in the area of Experimental Pharmacology, Clinical Pharmacy, Pharmaceutical Technology, Pharmacoeconomy, Pharmacognosy, Pharmaceutical ...