Journal of Educational Sciences
Vol 5. No. 2. April 2021

Teaching Structure with Molecular Visualization Tools. A Crash Course from Small Molecules to the HIV-1 Protease for Undergraduate Students

Mpeza, Paraskevi E. (Unknown)



Article Info

Publish Date
24 Apr 2021

Abstract

One of the challenges in the teaching of chemistry to students in higher education is their introduction to the visualization and molecular depiction software, deepening thus their understanding and creating new conceptions in the physical and biological sciences. This paper describes the implementation of a learning unit for 1st and 2nd semester undergraduate students (that were not previously exposed to molecular visualizations) in agricultural technology for chemistry and biochemistry courses respectively. A series of educational activities are presented beginning with the use of simple molecular models as plastic and wooden balls for atoms and sticks for bonds, to enhance the previous knowledge of the 2-D structural conformations. The students are introduced in depth to the theory of chemical bonding, molecular shapes, and polarity. This represents a continuum of increased complexity in inquiry-based learning, starting from simple molecules and ending with the exploration of the shape and function of a protein molecule, such as the human immunodeficiency virus (HIV)-1 protease; Thus easily leads to the study of the interactions between this protease and inhibitory drugs, via freely-available software tools. The gains in the students’ understanding and help for future courses and their career are analyzed.

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Journal Info

Abbrev

JES

Publisher

Subject

Religion Humanities Education Library & Information Science Other

Description

JES publishes original articles on the latest issues and trends occurring regionally and internationally in the educational sciences with the aim to advance our knowledge both in term of theory and practice. Moreover, this journal also covers the issues concerned with the following special sections: ...